DIFFERENTIAL GENE EXPRESSION AND CLONAL SELECTION DURING CELLULAR TRANSFORMATION INDUCED BY ADHESION DEPRIVATION

Differential gene expression and clonal selection during cellular transformation induced by adhesion deprivation

Abstract Background Anchorage independent growth is an important hallmark of oncogenic transformation.Previous Small dish studies have shown that when adhesion dependent fibroblasts were prevented from adhering to a substrate they underwent anoikis.In the present study we have demonstrated how anoikis resistant cells gain the transformation related

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LASP2 suppresses colorectal cancer progression through JNK/p38 MAPK pathway meditated epithelial-mesenchymal transition

Abstract Background LASP2 (LIM and SH3 Protein 2) is a small focal adhesion protein belongs to nebulin protein family.As the newest member of nebulette family, the function of LASP2 remains to Lead Wires be identified.Methods The relationship between LASP2 expression and clinical characteristics of CRC was analyzed in 89 paraffin-embedded archived

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Comparison of the Efficiency of Biopolymer Derived from Melocactus Sp and Aluminum Polichloride (PAC) in the Process of Crude Water Flocculation

Beginning to use new coagulants and flocculants for the treatment of drinking water is a necessity, to diminish the remains of metals in drinking water and in the residual sludges of the purification process; Aluminum sulfate, Jock iron chloride and aluminum polychloride are currently used for the coagulation and flocculation processes of the water

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Evaluating the risk of road traffic accidents (RTAs) and the reaction time of individuals with attention deficit disorder(ADD) in the virtual environment: A study protocol using the Sahand driving simulator and the Vienna test system

Background.Road Traffic Accidents (RTAs) are one of the essential causes of mortality;therefore, it is crucial to investigate the influencing factors.Studies indicate that drivers with attention deficit disorder have weaker VITAMIN C RADIANCE CITRUS FACIAL PEEL driving performance than others.Therefore, it is vital to evaluate their driving perform

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Assessing the water quality in urban river considering the influence of rainstorm flood: A case study of Handan city, China

The water quality of urban rivers is subject to fluctuation caused by rainstorm flood.The uncertainty of flooding in a dynamic environment brings about changes in river quality, presenting a significant challenge.Water samples were collected at 7 sampling sites in Handan City of China from January 2020 to August 2023, and 9 water quality parameters

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